At Lab Hours this past Wednesday, several people asked about text editing tools that would make working on Drupal theme files (page.tpl.php, template.php, style.css) easier. I recommended the tool I use, Komodo Edit. It dawned on me that I had written about this before-- last May.
Well, I've been using Komodo Edit since then for all my themeing except for CSS for which I have a better tool (the not-free CSS Edit). It's easy to use and has been a great utility. Since there is a brand-spanking-new version of Komodo Edit and it seems to be relevant for many, here is my original post with links to Komodo and other tools: http://www.advantagelabs.com/more_sophisticated_editing_tools_for_developing_drupal